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Spain's top goalscorers for the 2021-22 season, all club competitions. Updated to end of week 13. (09.11.21)
| Pichichi | League | Cup ** | Europe * | Total (Penalties) |
| Benzema (Real Madrid) | 10 | 0 | 4 | 14 (2) |
| Vinicius (Real Madrid) | 7 | 0 | 2 | 9 (0) |
| Luis Suárez (Atlético) | 7 | 0 | 1 | 8 (2) |
| De Tomás (Espanyol) | 7 | 0 | 0 | 7 (2) |
| Juanmi (Betis) | 5 | 0 | 2 | 7 (0) |
| Danjuma (Villarreal) | 5 | 0 | 2 | 7 (0) |
| Depay (Barcelona) | 6 | 0 | 0 | 6 (2) |
| Oyarzabal (Real Sociedad) | 6 | 0 | 0 | 6 (2) |
| Joselu (Alavés) | 5 | 0 | 0 | 5 (2) |
| Iago Aspas (Celta) | 5 | 0 | 0 | 5 (1) |
| Falcao (Rayo Vallecano) | 5 | 0 | 0 | 5 (0) |
| Borja Iglesias (Betis) | 3 | 0 | 2 | 5 (2) |
| Isak (Real Sociedad) | 3 | 0 | 2 | 5 (1) |
| Griezmann (Atlético) | 2 | 0 | 3 | 5 (0) |
| Willian José (Betis) | 4 | 0 | 0 | 4 (1) |
| Lozano (Cádiz) | 4 | 0 | 0 | 4 (0) |
| Santi Mina (Celta) | 4 | 0 | 0 | 4 (0) |
| Lucas Boyé (Elche) | 4 | 0 | 0 | 4 (0) |
| Morales (Levante) | 4 | 0 | 0 | 4 (0) |
| Alvaro García (Rayo) | 4 | 0 | 0 | 4 (0) |
| Lamela (Sevilla) | 4 | 0 | 0 | 4 (0) |
| Rafa Mir (Sevilla) | 4 | 0 | 0 | 4 (0) |
| Carlos Soler (Valencia) | 4 | 0 | 0 | 4 (3) |
| Hugo Duro (Valencia) | 4 | 0 | 0 | 4 (0) |
| Ansu Fati (Barcelona) | 3 | 0 | 1 | 4 (0) |
| Trigueros (Villarreal) | 3 | 0 | 1 | 4 (0) |
| Moreno (Villarreal) | 1 | 0 | 3 | 4 (0) |
* Includes European Super Cup
** Includes Spanish Super Cup