The three Spanish sides made it through to the last 32, Athletic Bilbao , Villarreal and Celta all finishing as runners up in their groups. The fixtures involving La Liga teams are set out below. (12.12.16)
16 Feb | Athletic Bilbao Merkis (OG), Aduríz, Williams |
3-2 | APOEL Nicosia Efrem, Gianniotas |
16 Feb | Villarreal |
0-4 | Roma Emerson, Dzeko (3) |
16 Feb | Celta |
0-1 | Shakhtar Donetsk Gustavo Blanco |
Second leg fixtures are as follows aet, After extra time; (teams qualifying in bold):
23 Feb | APOEL Nicosia Soteriou, Gianniotas (Pen) |
2-0 | Athletic Bilbao |
23 Feb | Roma |
0-1 | Villarreal Santos Borré |
23 Feb | Shakhtar Donetsk |
0-2 (aet) |
Celta Aspas (Pen), Cabral |